Natural killer activity in breast cancer patients

Role of natural killer activities in the
course of cancer progression in human remains one of the majorย issues in tumor immunology and immunotherapy.

This study is investigated the natural killerย activities of breast cancer patients. We found that natural killerย activities of peripheral-blood mononuclear cells (PBMCs)ย from breast cancer patients were substantially lower than fromย healthy individuals.
breast_cancer_01
NK activity of immuneย cells may play a critical role in tumor growth and metastasis,ย and that autologous activated NK cells could be a promisingย immunotherapeutic strategy against cancer either alone or inย combination with humanized anti-tumor antibodies asย a logical approach to the immunotherapy of cancer.

In summary, results suggest that NK activity of immune
cells may play a critical role in tumor growth and metastasis,
and that autologous activated NK cells could be a promising
immunotherapeutic strategy against cancer either alone or in
combination with humanized anti-tumor antibodies as
a logical approach to the immunotherapy of cancer.

Source : Biomedicine & Pharmacotherapy 63 (2009)

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