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Home / Academic journal / Immune System / Immunity / ์—ฐ๋ น์ฆ๊ฐ€์— ๋”ฐ๋ฅธ NK์„ธํฌ์˜ ํ™œ์„ฑํ™” ๋ฏผ๊ฐ๋„ ์—ฐ๊ตฌ

์—ฐ๋ น์ฆ๊ฐ€์— ๋”ฐ๋ฅธ NK์„ธํฌ์˜ ํ™œ์„ฑํ™” ๋ฏผ๊ฐ๋„ ์—ฐ๊ตฌ

— 2015-05-07

This report show the correlation of Natural Killer Cells Activity and aging.

Orgin :ย SENSITIVITY OF NATURAL KILLER CELLS TO ACTIVATION IN THE PROCESSย OF AGEING IS RELATED TO THE OXIDATIVE AND INFLAMMATORY STATUSย OF THE ELDERLY :ย L. KASZUBOWSKA1*, J.J. KACZOR2, L. HAK3, A. DETTLAFF-POKORA4, M. SZARYNSKA1, Z. KMIEC1 (2011)

JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY 2011, 62, 1, 101-109
www.jpp.krakow.pl

In conclusion, we have demonstrated that healthy ageing of
nonagenarians was associated with high activity of the NK cells that was related to the oxidative-inflammatory status.
Measurements of the serum indices of the oxidative state, levels of proinflammatory cytokines and NK cell activity may prove useful data to assess successful ageing.
DISCUSSION : Ageing is accompanied by the alterations of both adaptive and innate immunity. The increase of serum levels of IL-6, TNF-a and other inflammatory mediators results in a state of a chronic low-grade inflammation.

 

SENSITIVITY-OF-NATURAL-KILLER-CELLS-TO-ACTIVATION SENSITIVITY-OF-NATURAL-KILLER-CELLS-TO-ACTIVATION_02

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