Hematopoietic Stem Cell

Hematopoietic Stem Cells (HSCs)

Hematopoietic Stem Cells have been used in the traditional treatment for lymphoma and severe autoimmune through bone marrow transplantation in 40 years ago. Stem cells that turn into blood cells are called hematopoietic stem cells. These cells are capable of developing into the three types of blood cells:

  1. red blood cells that carry oxygen
  2. white blood cells that fight infection
  3. platelets that help blood to clot

Hematopoietic stem cells can be found in bone marrow (the spongy tissue inside bones), the bloodstream, or the umbilical cord blood of newborn babies. A stem cell transplant (sometimes called a bone marrow transplant) can replenish a patient’s supply of healthy hematopoietic stem cells after they have been depleted. It’s used to treat a wide range of diseases, including cancers like leukemia, lymphoma, neuroblastoma, Wilms tumor, and certain testicular or ovarian cancers; blood disorders; immune system diseases; and bone marrow syndromes. Transplanted hematopoietic stem cells are put into the bloodstream through an intravenous (IV) line, much like a blood transfusion. Once in the body, they can produce healthy new blood and immune system cells.

 

1. WHO • Adult
2. WHAT • Bone-marrow, Peripheral Blood by apheresis, Cord Blood(Tissue)
3. WHEN • Always in good health or biopsy for patient’s disease diagnosis.
4. WHERE • Bone-marrow puncture, Apheresis(leukapheresis) after injection G-CSF, Cord
• Storage : companies, hospitals, laboratories
* G-csf : granulocyte colony stimulating factor
5. WHY The reason to collect and storage
• for public – research
• for private – self health against diseases
6. HOW • Plantation after cultivation or non-cultivation
7. Application (included diseases under investigation)
• Malignant lymphoma, Multiple myeloma, Acute myeloid leukemia, Acute lymphoblastic leukemia, Breast Cancer, Ovarian cancer, Germinoma, Neuroblastoma, Ewing’s tumor, Wilm’s tumor, Osteosarcoma, Autoimmune diseases in conventional treatment fail(Systemic sclerosis, Rheumatoid arthritis, Multiple sclerosis, Systemic lupus erythematous) Myocardial infarction, Diabetes, Cerebral infarction, Spinal cord injury, Liver cirrhosis, Ischemic Peripheral Vascular Disease, etc.

Hematopoietic_StemCell

[Illust-04:Types of Hematopoietic Stem Cell by allstemcells.com

Types of Stem Cell Transplants

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