Research Papers

Recall responses by human NK cells

2019-05-23 15:11

One of the traditional dividing lines separating innate and adaptive immunity is the restriction of immune memory to adaptive immune cells. However, accumulating evidence in animal models has suggested that memory responses can be evoked in natural killer (NK) cells. Nikzad et al. asked whether human NK cells also exhibit memory responses.

They analyzed NK cells recovered from humanized mice and NK cells found in the viral antigen-challenged skin of adult volunteers who had chickenpox as children. Antigen-specific recall responses by human NK cells were observed in both experimental systems. Thus, human NK memory responses contribute to host protection after vaccinations or natural infections. 봊RF

Sci. Immunol. 4, eaat8116 (2019)

Source :혻Science Magazine - May 2019
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