Natural killer activity in breast cancer patients
— 2015-05-21Role of natural killer activities in the course of cancer progression in human remains one of the major issues in tumor immunology and immunotherapy.
This study is investigated the natural killer activities of breast cancer patients. We found that natural killer activities of peripheral-blood mononuclear cells (PBMCs) from breast cancer patients were substantially lower than from healthy individuals.
NK activity of immune cells may play a critical role in tumor growth and metastasis, and that autologous activated NK cells could be a promising immunotherapeutic strategy against cancer either alone or in combination with humanized anti-tumor antibodies as a logical approach to the immunotherapy of cancer.
In summary, results suggest that NK activity of immune cells may play a critical role in tumor growth and metastasis, and that autologous activated NK cells could be a promising immunotherapeutic strategy against cancer either alone or in combination with humanized anti-tumor antibodies as a logical approach to the immunotherapy of cancer.
Source : Biomedicine & Pharmacotherapy 63 (2009)
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