Natural killer activity in breast cancer patients

Role of natural killer activities in the course of cancer progression in human remains one of the major혻issues in tumor immunology and immunotherapy.

This study is investigated the natural killer혻activities of breast cancer patients. We found that natural killer혻activities of peripheral-blood mononuclear cells (PBMCs)혻from breast cancer patients were substantially lower than from혻healthy individuals.

breast_cancer_01

NK activity of immune혻cells may play a critical role in tumor growth and metastasis,혻and that autologous activated NK cells could be a promising혻immunotherapeutic strategy against cancer either alone or in혻combination with humanized anti-tumor antibodies as혻a logical approach to the immunotherapy of cancer.

In summary, results suggest that NK activity of immune cells may play a critical role in tumor growth and metastasis, and that autologous activated NK cells could be a promising immunotherapeutic strategy against cancer either alone or in combination with humanized anti-tumor antibodies as a logical approach to the immunotherapy of cancer.



Source : Biomedicine & Pharmacotherapy 63 (2009)

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